Motif ID: HOX{A6,A7,B6,B7}.p2

Z-value: 2.819


Transcription factors associated with HOX{A6,A7,B6,B7}.p2:

Gene SymbolEntrez IDGene Name
HOXA6 3203 homeobox A6
HOXA7 3204 homeobox A7
HOXB6 3216 homeobox B6
HOXB7 3217 homeobox B7

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HOXA7chr7_-_271626880.621.0e-02Click!
HOXB7chr17_-_440429240.601.5e-02Click!
HOXB6chr17_-_440373320.533.6e-02Click!
HOXA6chr7_-_271538920.449.1e-02Click!


Activity profile for motif HOX{A6,A7,B6,B7}.p2.

activity profile for motif HOX{A6,A7,B6,B7}.p2


Sorted Z-values histogram for motif HOX{A6,A7,B6,B7}.p2

Sorted Z-values for motif HOX{A6,A7,B6,B7}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A6,A7,B6,B7}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_14076901 12.318 NFIB
nuclear factor I/B
chr7_-_41709191 7.727 NM_002192
INHBA
inhibin, beta A
chr9_+_108726257 5.413 ZNF462
zinc finger protein 462
chr2_+_101874809 5.181 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr14_+_51025604 5.132 NM_001042481
FRMD6
FERM domain containing 6
chr1_+_168898898 4.793 PRRX1
paired related homeobox 1
chr3_-_64186151 4.759 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr7_-_27133163 4.564 NM_153631
HOXA3
homeobox A3
chr8_-_122722674 4.549 NM_005328
HAS2
hyaluronan synthase 2
chr7_-_27171648 4.461 HOXA9
homeobox A9
chr2_+_101874765 4.367 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr7_-_13992351 4.354 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr7_-_27171673 4.313 NM_152739
HOXA9
homeobox A9
chr3_+_161040343 4.209 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr12_-_16652202 4.207 NM_001001395
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_+_161040439 4.133 SCHIP1
schwannomin interacting protein 1
chr3_-_188935363 4.111 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr2_-_160764819 3.922 NM_000888
ITGB6
integrin, beta 6
chr11_+_101488380 3.918 NM_001195045
YAP1
Yes-associated protein 1
chr10_+_69539255 3.850 NM_032578
MYPN
myopalladin
chr10_-_33663305 3.684 NRP1
neuropilin 1
chr10_-_126706442 3.528 NM_022802
CTBP2
C-terminal binding protein 2
chr7_-_27171600 3.420 HOXA9
homeobox A9
chr2_+_166137091 3.164 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr7_-_107667728 3.145 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr2_-_160765008 3.101 ITGB6
integrin, beta 6
chr11_+_120478584 3.072 NM_005422
TECTA
tectorin alpha
chr8_+_32623792 3.050 NM_013959
NRG1
neuregulin 1
chr7_-_111216180 3.039 DOCK4
dedicator of cytokinesis 4
chr1_+_84402962 3.005 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_-_90100733 2.997 NM_001920
DCN
decorin
chr3_-_71262426 2.935 FOXP1
forkhead box P1
chr7_+_134114912 2.924 CALD1
caldesmon 1
chr9_+_27099138 2.894 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr2_-_160838397 2.889 RBMS1
RNA binding motif, single stranded interacting protein 1
chr4_-_87989291 2.832 NM_197965
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr11_-_128567302 2.825 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr17_-_36376663 2.811 NM_213656
KRT39
keratin 39
chr6_+_45404031 2.791 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr15_+_69626594 2.719 THSD4
thrombospondin, type I, domain containing 4
chr3_-_188946168 2.706 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr18_+_57308754 2.696 NM_031891
CDH20
cadherin 20, type 2
chr12_-_88270128 2.629 DUSP6
dual specificity phosphatase 6
chr17_-_44037332 2.579 NM_018952
HOXB6
homeobox B6
chr17_-_44042924 2.557 HOXB7
homeobox B7
chr5_+_174084137 2.553 NM_002449
MSX2
msh homeobox 2
chr16_+_85169615 2.546 NM_005250
FOXL1
forkhead box L1
chr1_+_181380837 2.545 LAMC1
laminin, gamma 1 (formerly LAMB2)
chr7_+_134226727 2.518 CALD1
caldesmon 1
chr2_+_66516196 2.479 MEIS1
Meis homeobox 1
chr3_+_158637273 2.465 NM_002852
PTX3
pentraxin 3, long
chr9_+_108665168 2.458 NM_021224
ZNF462
zinc finger protein 462
chr5_-_58331515 2.455 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_55489973 2.443 WNT5A
wingless-type MMTV integration site family, member 5A
chr5_+_71538456 2.439 MAP1B
microtubule-associated protein 1B
chr4_+_88939725 2.439 NM_004967
IBSP
integrin-binding sialoprotein
chr22_-_34566367 2.437 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr3_-_71376919 2.424 FOXP1
forkhead box P1
chr14_+_100365390 2.420 MEG3
maternally expressed 3 (non-protein coding)
chr7_-_27149750 2.394 NM_019102
HOXA5
homeobox A5
chr9_-_116920232 2.386 NM_002160
TNC
tenascin C
chr4_+_109033868 2.385 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr19_+_12995782 2.379 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr6_-_138862271 2.355 NM_001144060
NHSL1
NHS-like 1
chr6_+_21701942 2.348 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr6_-_170441493 2.347 NM_005618
DLL1
delta-like 1 (Drosophila)
chr3_-_102522093 2.333 NM_016247
IMPG2
interphotoreceptor matrix proteoglycan 2
chr17_-_10393664 2.319 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chr9_-_13240313 2.309 NM_003829
MPDZ
multiple PDZ domain protein
chr5_+_166644420 2.293 NM_001122679
ODZ2
odz, odd Oz/ten-m homolog 2 (Drosophila)
chr1_-_201321999 2.290 NM_002479
MYOG
myogenin (myogenic factor 4)
chr12_-_15757114 2.286 EPS8
epidermal growth factor receptor pathway substrate 8
chr8_+_32698892 2.271 NM_001159996
NRG1
neuregulin 1
chr9_-_21472311 2.250 NM_176891
IFNE
interferon, epsilon
chr7_-_83662152 2.246 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr6_+_136214495 2.244 NM_018945
PDE7B
phosphodiesterase 7B
chr14_-_53493198 2.228 NM_001202
NM_130850
BMP4

bone morphogenetic protein 4

chr13_-_101852028 2.224 NM_175929
FGF14
fibroblast growth factor 14
chr2_-_224175339 2.211 SCG2
secretogranin II
chr4_-_41579325 2.210


chr2_-_189752575 2.184 NM_000393
COL5A2
collagen, type V, alpha 2
chr5_+_36642424 2.175 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr17_-_44026321 2.164 HOXB5
homeobox B5
chr13_-_37070862 2.155 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr2_+_210152609 2.139 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr7_+_134226690 2.119 NM_033139
NM_033140
CALD1

caldesmon 1

chr2_+_234490781 2.099 NM_024080
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr11_-_27698800 2.097 NM_001143805
NM_001143806
NM_170732
BDNF


brain-derived neurotrophic factor


chr3_-_150578207 2.084 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr12_-_88270375 2.082 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr18_-_21185968 2.078 ZNF521
zinc finger protein 521
chr8_-_93176618 2.074 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr4_-_184480572 2.065 NM_001185149
CLDN24
claudin 24
chr12_-_90100710 2.057 DCN
decorin
chr2_-_40510923 2.031 NM_001112800
NM_001112801
NM_021097
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr2_-_224175293 2.029 SCG2
secretogranin II
chr12_-_88270369 2.005 DUSP6
dual specificity phosphatase 6
chr2_-_215953818 1.995 FN1
fibronectin 1
chr3_-_150578148 1.982 TM4SF1
transmembrane 4 L six family member 1
chr4_+_81325447 1.966 NM_020226
PRDM8
PR domain containing 8
chr17_-_36418869 1.954 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr2_-_55090759 1.941 NM_007008
RTN4
reticulon 4
chr12_+_79362256 1.940 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr17_-_44026042 1.915 NM_002147
HOXB5
homeobox B5
chr13_+_100902942 1.911 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr10_-_29963906 1.907 NM_021738
SVIL
supervillin
chr1_-_94359266 1.903 NM_000350
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr4_-_159312973 1.902 FAM198B
family with sequence similarity 198, member B
chr1_-_201321711 1.897 MYOG
myogenin (myogenic factor 4)
chr7_-_115458064 1.884 TFEC
transcription factor EC
chr5_-_59819642 1.877 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chrX_-_10495476 1.865 NM_001193278
NM_001193279
NM_001193280
NM_001193281
MID1



midline 1 (Opitz/BBB syndrome)



chr14_-_80934523 1.859 NM_033104
STON2
stonin 2
chr3_-_55490401 1.857 WNT5A
wingless-type MMTV integration site family, member 5A
chr6_-_169395972 1.855 NM_003247
THBS2
thrombospondin 2
chr17_+_39990124 1.851 NM_001466
FZD2
frizzled homolog 2 (Drosophila)
chr7_+_18501876 1.847 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr5_-_1935764 1.839 NM_016358
IRX4
iroquois homeobox 4
chr12_-_90100679 1.838 DCN
decorin
chr8_-_49996353 1.828 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr8_+_77756077 1.820 ZFHX4
zinc finger homeobox 4
chr4_+_169654742 1.816 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr9_-_14388981 1.814 NM_001190738
NFIB
nuclear factor I/B
chr2_+_121271336 1.810 NM_005270
GLI2
GLI family zinc finger 2
chr2_-_190635566 1.810 NM_005259
MSTN
myostatin
chr20_-_33489383 1.802 NM_000557
GDF5
growth differentiation factor 5
chr12_+_32546243 1.801 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr5_+_140723939 1.801 NM_018918
NM_032054
PCDHGA5

protocadherin gamma subfamily A, 5

chr3_+_130730171 1.796 NM_000539
RHO
rhodopsin
chr3_-_150578103 1.794 TM4SF1
transmembrane 4 L six family member 1
chr2_-_133145539 1.794 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr21_-_38792173 1.793 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr7_-_115458010 1.791 NM_001018058
NM_012252
TFEC

transcription factor EC

chr14_+_100365162 1.791 MEG3
maternally expressed 3 (non-protein coding)
chr10_+_118073929 1.768 NM_198515
C10orf96
chromosome 10 open reading frame 96
chr2_-_224175386 1.761 NM_003469
SCG2
secretogranin II
chr3_+_160269734 1.755 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr17_-_43977273 1.755 NM_002145
HOXB2
homeobox B2
chr20_+_19903778 1.754 RIN2
Ras and Rab interactor 2
chr9_-_94226380 1.742 NM_005014
OMD
osteomodulin
chr8_+_104900591 1.735 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr2_-_164300758 1.728 NM_018086
FIGN
fidgetin
chr2_-_215967442 1.711 FN1
fibronectin 1
chr8_+_77756061 1.706 NM_024721
ZFHX4
zinc finger homeobox 4
chr7_+_134114701 1.704 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr3_-_79899748 1.702 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr9_+_102380156 1.697 NM_001018116
MURC
muscle-related coiled-coil protein
chr6_+_121798443 1.691 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr2_-_183095308 1.686 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr6_-_152744022 1.679 SYNE1
spectrin repeat containing, nuclear envelope 1
chr4_+_41309668 1.677 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr12_+_88268845 1.672 LOC100131490
hypothetical LOC100131490
chr4_+_54790190 1.670 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr18_-_21186107 1.650 NM_015461
ZNF521
zinc finger protein 521
chr6_-_138935359 1.633 NM_020464
NHSL1
NHS-like 1
chr2_+_66516020 1.632 NM_002398
MEIS1
Meis homeobox 1
chr3_-_158695832 1.626 NM_001167917
VEPH1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr12_+_52708460 1.600 NM_004503
HOXC6
homeobox C6
chrX_+_11221453 1.599 NM_001142
NM_182680
NM_182681
AMELX


amelogenin, X-linked


chr10_+_124310170 1.597 NM_004406
NM_007329
NM_017579
DMBT1


deleted in malignant brain tumors 1


chr3_+_116824840 1.595 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr6_+_12824873 1.587 PHACTR1
phosphatase and actin regulator 1
chr12_+_50633430 1.583 NM_020327
ACVR1B
activin A receptor, type IB
chr11_-_27679617 1.579 NM_170733
BDNF
brain-derived neurotrophic factor
chr8_-_18710575 1.578 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr4_+_88790477 1.572 NM_001079911
NM_004407
DMP1

dentin matrix acidic phosphoprotein 1

chr3_-_158704056 1.571 NM_001167915
NM_001167916
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chrX_+_102471769 1.567 NM_152278
TCEAL7
transcription elongation factor A (SII)-like 7
chr19_-_54835162 1.565 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr9_+_2707525 1.556 NM_133497
KCNV2
potassium channel, subfamily V, member 2
chr4_-_141293572 1.551 MAML3
mastermind-like 3 (Drosophila)
chr2_-_151052391 1.548 NM_005168
RND3
Rho family GTPase 3
chr6_-_138862273 1.522


chr11_-_85103438 1.518 NM_032379
SYTL2
synaptotagmin-like 2
chr4_+_54790020 1.518 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr20_-_14266200 1.511 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr7_+_28418668 1.491 NM_182898
CREB5
cAMP responsive element binding protein 5
chr6_+_12398514 1.489 NM_001168319
NM_001955
EDN1

endothelin 1

chr15_-_31147376 1.488 NM_001103184
FMN1
formin 1
chr5_+_127012611 1.483 NM_001048252
CTXN3
cortexin 3
chr17_-_10362583 1.481 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr5_-_58918031 1.480 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_+_33306652 1.479 HIPK3
homeodomain interacting protein kinase 3
chr1_+_203106600 1.473 NFASC
neurofascin
chr2_-_215949566 1.459 FN1
fibronectin 1
chr13_-_85271329 1.457 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr8_+_70541631 1.444 SULF1
sulfatase 1
chr5_-_145232723 1.436 NM_001080516
GRXCR2
glutaredoxin, cysteine rich 2
chr9_-_14712669 1.432 NM_005454
CER1
cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)
chr11_-_85107569 1.422 NM_206929
SYTL2
synaptotagmin-like 2
chr5_-_76970264 1.422 NM_032109
OTP
orthopedia homeobox
chr7_+_134114957 1.419 CALD1
caldesmon 1
chr3_-_74652952 1.415 NM_020872
CNTN3
contactin 3 (plasmacytoma associated)
chr5_+_36642213 1.409 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr5_+_34723420 1.401 NM_001145523
RAI14
retinoic acid induced 14
chr11_+_20000938 1.401 NAV2
neuron navigator 2
chr5_+_92944680 1.401 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr2_+_210152399 1.397 MAP2
microtubule-associated protein 2
chr12_+_118100977 1.395 NM_014365
HSPB8
heat shock 22kDa protein 8
chr17_-_44006808 1.391 NM_002146
HOXB3
homeobox B3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.36 5.19e-38 GO:0032501 multicellular organismal process
1.51 2.61e-32 GO:0048731 system development
1.46 6.47e-31 GO:0048856 anatomical structure development
1.43 2.36e-29 GO:0007275 multicellular organismal development
1.40 2.71e-28 GO:0032502 developmental process
1.63 4.68e-23 GO:0009653 anatomical structure morphogenesis
1.53 9.86e-22 GO:0048513 organ development
1.60 1.73e-20 GO:0007399 nervous system development
1.44 4.59e-16 GO:0030154 cell differentiation
1.72 9.82e-16 GO:0048699 generation of neurons
1.69 1.21e-15 GO:0022008 neurogenesis
1.43 2.54e-15 GO:0048869 cellular developmental process
1.67 6.76e-14 GO:0009888 tissue development
1.45 1.01e-13 GO:0003008 system process
1.73 7.28e-13 GO:0030182 neuron differentiation
2.07 5.01e-12 GO:0001501 skeletal system development
2.67 7.10e-12 GO:0007156 homophilic cell adhesion
3.18 1.31e-11 GO:0048706 embryonic skeletal system development
1.67 1.41e-11 GO:2000026 regulation of multicellular organismal development
1.60 2.40e-11 GO:0050793 regulation of developmental process
1.69 2.56e-11 GO:0009790 embryo development
2.22 3.44e-11 GO:0003002 regionalization
1.74 3.54e-11 GO:0009887 organ morphogenesis
1.69 4.87e-11 GO:0045595 regulation of cell differentiation
1.63 3.57e-10 GO:0007155 cell adhesion
1.63 3.57e-10 GO:0022610 biological adhesion
1.91 7.40e-10 GO:0048598 embryonic morphogenesis
1.17 2.08e-09 GO:0050896 response to stimulus
1.43 3.27e-09 GO:0050877 neurological system process
2.38 3.50e-09 GO:0048562 embryonic organ morphogenesis
1.74 9.40e-09 GO:0000904 cell morphogenesis involved in differentiation
1.93 9.64e-09 GO:0060284 regulation of cell development
1.53 1.06e-08 GO:0048468 cell development
1.66 1.88e-08 GO:0000902 cell morphogenesis
1.43 3.92e-08 GO:0051239 regulation of multicellular organismal process
1.70 4.83e-08 GO:0007417 central nervous system development
1.23 4.90e-08 GO:0023052 signaling
1.82 5.73e-08 GO:0009792 embryo development ending in birth or egg hatching
1.81 1.31e-07 GO:0043009 chordate embryonic development
2.31 1.33e-07 GO:0045165 cell fate commitment
1.61 1.38e-07 GO:0030030 cell projection organization
1.64 1.51e-07 GO:0048666 neuron development
1.90 1.63e-07 GO:0016337 cell-cell adhesion
1.74 1.72e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.69 1.78e-07 GO:0048858 cell projection morphogenesis
1.47 1.88e-07 GO:0009605 response to external stimulus
1.83 2.37e-07 GO:0007389 pattern specification process
3.11 2.55e-07 GO:0048704 embryonic skeletal system morphogenesis
1.75 2.67e-07 GO:0007409 axonogenesis
1.71 2.69e-07 GO:0048646 anatomical structure formation involved in morphogenesis
1.60 2.88e-07 GO:0032989 cellular component morphogenesis
1.72 2.94e-07 GO:0048812 neuron projection morphogenesis
1.67 3.53e-07 GO:0032990 cell part morphogenesis
1.67 6.65e-07 GO:0031175 neuron projection development
2.20 7.09e-07 GO:0009952 anterior/posterior pattern formation
1.90 8.46e-07 GO:0061061 muscle structure development
1.82 1.01e-06 GO:0007411 axon guidance
1.92 1.19e-06 GO:0045596 negative regulation of cell differentiation
2.08 1.20e-06 GO:0048732 gland development
1.67 1.29e-06 GO:0072358 cardiovascular system development
1.67 1.29e-06 GO:0072359 circulatory system development
1.77 1.80e-06 GO:0007420 brain development
1.96 1.84e-06 GO:0048568 embryonic organ development
1.87 2.09e-06 GO:0007423 sensory organ development
1.45 2.98e-06 GO:0042127 regulation of cell proliferation
2.27 5.24e-06 GO:0048705 skeletal system morphogenesis
1.47 6.73e-06 GO:0040011 locomotion
1.47 9.07e-06 GO:0007600 sensory perception
1.43 1.39e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.21 1.55e-05 GO:0007165 signal transduction
1.41 2.45e-05 GO:0007154 cell communication
1.81 2.62e-05 GO:0051960 regulation of nervous system development
1.48 2.95e-05 GO:0007267 cell-cell signaling
1.75 3.02e-05 GO:0051093 negative regulation of developmental process
1.58 3.37e-05 GO:0008284 positive regulation of cell proliferation
1.76 3.83e-05 GO:0022603 regulation of anatomical structure morphogenesis
1.51 3.96e-05 GO:0010628 positive regulation of gene expression
1.23 5.43e-05 GO:0048518 positive regulation of biological process
2.95 6.54e-05 GO:0001764 neuron migration
1.62 6.73e-05 GO:0051094 positive regulation of developmental process
1.47 7.15e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
1.51 8.70e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.24 9.68e-05 GO:0048522 positive regulation of cellular process
1.50 1.09e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.93 1.31e-04 GO:0007517 muscle organ development
1.99 1.32e-04 GO:0030900 forebrain development
2.12 1.75e-04 GO:0060537 muscle tissue development
1.90 2.16e-04 GO:0045664 regulation of neuron differentiation
1.12 2.25e-04 GO:0050794 regulation of cellular process
1.24 2.43e-04 GO:0048519 negative regulation of biological process
1.81 2.47e-04 GO:0050767 regulation of neurogenesis
2.04 2.52e-04 GO:0043062 extracellular structure organization
1.55 2.59e-04 GO:0048585 negative regulation of response to stimulus
1.61 3.31e-04 GO:0016477 cell migration
2.50 3.37e-04 GO:0022612 gland morphogenesis
1.25 3.42e-04 GO:0048523 negative regulation of cellular process
1.59 3.76e-04 GO:0032583 regulation of gene-specific transcription
2.13 4.91e-04 GO:0014706 striated muscle tissue development
1.67 5.48e-04 GO:0045597 positive regulation of cell differentiation
1.56 5.54e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.56 6.40e-04 GO:0048870 cell motility
1.56 6.40e-04 GO:0051674 localization of cell
1.41 6.53e-04 GO:0031328 positive regulation of cellular biosynthetic process
2.41 6.63e-04 GO:0021953 central nervous system neuron differentiation
1.43 7.58e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.50 7.86e-04 GO:0006928 cellular component movement
2.07 7.99e-04 GO:0001503 ossification
2.16 8.47e-04 GO:0043583 ear development
1.73 9.41e-04 GO:0001568 blood vessel development
1.40 9.54e-04 GO:0009891 positive regulation of biosynthetic process
1.42 1.01e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.45 1.38e-03 GO:0051254 positive regulation of RNA metabolic process
1.69 1.48e-03 GO:0001944 vasculature development
1.27 1.53e-03 GO:0023051 regulation of signaling
2.79 1.64e-03 GO:0001649 osteoblast differentiation
1.61 1.92e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
3.28 2.01e-03 GO:0007602 phototransduction
1.10 3.00e-03 GO:0050789 regulation of biological process
2.54 3.42e-03 GO:0009582 detection of abiotic stimulus
1.37 4.17e-03 GO:0006351 transcription, DNA-dependent
1.77 4.19e-03 GO:0048514 blood vessel morphogenesis
3.05 4.44e-03 GO:0051153 regulation of striated muscle cell differentiation
2.47 4.63e-03 GO:0007519 skeletal muscle tissue development
2.95 4.72e-03 GO:0009583 detection of light stimulus
1.67 5.49e-03 GO:0035295 tube development
1.48 5.94e-03 GO:0006935 chemotaxis
1.48 5.94e-03 GO:0042330 taxis
2.40 6.02e-03 GO:0060538 skeletal muscle organ development
1.09 7.19e-03 GO:0065007 biological regulation
1.55 7.75e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.63 7.81e-03 GO:0048729 tissue morphogenesis
1.72 1.06e-02 GO:0007601 visual perception
1.72 1.06e-02 GO:0050953 sensory perception of light stimulus
1.24 1.06e-02 GO:0007166 cell surface receptor linked signaling pathway
1.90 1.07e-02 GO:0009416 response to light stimulus
1.27 1.19e-02 GO:0009966 regulation of signal transduction
1.14 1.35e-02 GO:0051716 cellular response to stimulus
1.75 1.40e-02 GO:0008544 epidermis development
1.69 1.44e-02 GO:0007507 heart development
1.50 1.45e-02 GO:0023057 negative regulation of signaling
2.35 1.47e-02 GO:0051147 regulation of muscle cell differentiation
1.54 1.50e-02 GO:0060429 epithelium development
1.21 1.50e-02 GO:0042221 response to chemical stimulus
1.31 1.58e-02 GO:0010646 regulation of cell communication
2.13 1.65e-02 GO:0021537 telencephalon development
2.03 1.78e-02 GO:0048736 appendage development
2.03 1.78e-02 GO:0060173 limb development
1.52 1.86e-02 GO:0009968 negative regulation of signal transduction
1.30 1.90e-02 GO:0010604 positive regulation of macromolecule metabolic process
3.12 2.15e-02 GO:0060688 regulation of morphogenesis of a branching structure
2.10 2.21e-02 GO:0048839 inner ear development
1.28 2.22e-02 GO:0009893 positive regulation of metabolic process
1.22 2.38e-02 GO:0048583 regulation of response to stimulus
2.20 2.50e-02 GO:0042471 ear morphogenesis
1.69 2.63e-02 GO:0002009 morphogenesis of an epithelium
1.81 2.67e-02 GO:0001525 angiogenesis
2.28 2.98e-02 GO:0009953 dorsal/ventral pattern formation
2.61 3.47e-02 GO:0048663 neuron fate commitment
2.90 4.13e-02 GO:0050777 negative regulation of immune response
1.44 4.21e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.46 4.28e-02 GO:0070848 response to growth factor stimulus
1.28 4.44e-02 GO:0031325 positive regulation of cellular metabolic process
2.00 4.49e-02 GO:0035107 appendage morphogenesis
2.00 4.49e-02 GO:0035108 limb morphogenesis
1.47 4.82e-02 GO:0010648 negative regulation of cell communication

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.31 2.60e-20 GO:0005886 plasma membrane
1.29 2.67e-19 GO:0071944 cell periphery
2.08 1.77e-13 GO:0005578 proteinaceous extracellular matrix
1.35 4.38e-12 GO:0044459 plasma membrane part
1.92 7.58e-12 GO:0031012 extracellular matrix
1.53 1.26e-11 GO:0044421 extracellular region part
1.34 1.20e-10 GO:0005576 extracellular region
1.56 7.65e-07 GO:0030054 cell junction
1.68 9.91e-07 GO:0045202 synapse
2.27 4.33e-06 GO:0044420 extracellular matrix part
1.64 9.69e-06 GO:0043005 neuron projection
1.39 8.10e-05 GO:0042995 cell projection
1.41 9.28e-05 GO:0005615 extracellular space
1.88 1.25e-04 GO:0030424 axon
1.09 4.27e-03 GO:0016020 membrane
2.50 6.45e-03 GO:0034774 secretory granule lumen
1.56 7.60e-03 GO:0044456 synapse part
2.42 8.48e-03 GO:0031983 vesicle lumen
2.73 9.12e-03 GO:0005581 collagen
1.87 1.17e-02 GO:0043292 contractile fiber
1.88 1.41e-02 GO:0030016 myofibril
2.40 1.43e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
2.44 1.64e-02 GO:0031093 platelet alpha granule lumen
1.60 2.00e-02 GO:0016323 basolateral plasma membrane
2.26 2.15e-02 GO:0031091 platelet alpha granule
1.70 2.43e-02 GO:0005882 intermediate filament
1.24 2.57e-02 GO:0031226 intrinsic to plasma membrane
1.21 3.49e-02 GO:0005856 cytoskeleton
1.09 4.57e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.76 3.21e-15 GO:0043565 sequence-specific DNA binding
1.61 1.73e-14 GO:0001071 nucleic acid binding transcription factor activity
1.61 1.73e-14 GO:0003700 sequence-specific DNA binding transcription factor activity
1.73 3.11e-13 GO:0005509 calcium ion binding
1.51 3.75e-10 GO:0030528 transcription regulator activity
1.39 1.45e-05 GO:0005102 receptor binding
1.92 3.07e-04 GO:0008083 growth factor activity
1.45 4.73e-04 GO:0005198 structural molecule activity
1.23 4.74e-04 GO:0004871 signal transducer activity
1.23 4.74e-04 GO:0060089 molecular transducer activity
1.28 2.43e-03 GO:0004888 transmembrane receptor activity
1.24 3.81e-03 GO:0004872 receptor activity
1.81 5.21e-03 GO:0001871 pattern binding
1.81 5.21e-03 GO:0030247 polysaccharide binding
1.56 6.09e-03 GO:0003779 actin binding
1.89 8.88e-03 GO:0060090 binding, bridging
1.81 1.18e-02 GO:0005539 glycosaminoglycan binding
2.33 3.20e-02 GO:0004879 ligand-dependent nuclear receptor activity
2.36 3.73e-02 GO:0003707 steroid hormone receptor activity
2.05 4.27e-02 GO:0005201 extracellular matrix structural constituent
1.84 4.90e-02 GO:0030674 protein binding, bridging